Yan Kai
  • Bio
  • News
  • Papers
  • Blog
ESC

Searching...

No results found

↑↓ Navigate ↵ Select
Powered by Hugo Blox
  • News
    • I presented our work on HbF induction by BMS-986470 at EHA 2026 in Stockholm, Sweden.
    • Our multi-omics study revealing an RNA-seq Ikaros/Aiolos signature for CELMoD response in multiple myeloma is accepted at AACR 2026!
    • We are excited to announce ContextMap!
    • Catch me at NeurIPS 2025!
    • Our paper on Golcadomide is published in Blood Cancer Discovery
  • Publications
    • [24] Development of a novel Ikaros/Aiolos transcriptional signature and correlation with patient response in multiple myeloma patients treated with CELMoDs
    • [23] Golcadomide: An Oral CELMoD Agent Targeting IKZF1/3 For Diffuse Large B-Cell Lymphoma
    • [22] O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer
    • [21] Matrin3 mediates differentiation through stabilizing chromatin loop-domain interactions and YY1 mediated enhancer-promoter interactions
    • [20] Mechanistic and kinetic insights into Transcription factor biology via acute protein depletion
    • [19] Identifying Quantitatively Differential Chromosomal Compartmentalization Changes and Their Biological Significance from Hi-C data using DARIC
    • [18] MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
    • [17] Lysine methyltransferase Kmt2d regulates naive CD8+ T cell activation-induced survival
    • [16] A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia
    • [15] Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
    • [14] Transcription factor competition at the γ-globin promoters controls hemoglobin switching
    • [13] Mapping the evolving landscape of super-enhancers during cell differentiation
    • [12] Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture
    • [11] BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice
    • [10] Secretome profiling identifies neuron-derived neurotrophic factor as a tumor-suppressive factor in lung cancer
    • [9] miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer
    • [8] Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors
    • [7] Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance
    • [6] DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer
    • [5] Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features
    • [4] dbVar structural variant cluster set for data analysis and variant comparison
    • [3] Lysine-specific histone demethylases in normal and malignant hematopoiesis
    • [2] Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis
    • [1] Highly stable and AC electric field-activated electrorheological fluid based on mesoporous silica-coated graphene nanosheets
    • [25] DISSECTING THE MOLECULAR BASIS OF POTENT HBF INDUCTION BY BMS-986470: A MECHANISTIC STUDY OF ZBTB7A/WIZ DUAL DEGRADATION
  • Blog
    • Introducing ContextMap: Session Intelligence for Claude Code
  • Projects
  • Papers
  • Recent & Upcoming Talks

Catch me at NeurIPS 2025!

Dec 3, 2025·
Yan Kai
Yan Kai
· 1 min read
news

I’ll be attending NeurIPS 2025! Looking forward to connecting with the community and discussing how AI is transforming drug discovery and genomics research!

NeurIPS 2025

Last updated on Dec 3, 2025
Yan Kai
Authors
Yan Kai
Principal Scientist, AI in Drug Discovery
← We are excited to announce ContextMap! Feb 21, 2026
Our paper on Golcadomide is published in Blood Cancer Discovery Nov 5, 2025 →

© 2026 Yan Kai. This work is licensed under CC BY NC ND 4.0

Made with Hugo Blox — Open Source. Build yours →